I was saddened last month to learn of the untimely death of my friend Seth Roberts, a highly original thinker on matters that lie at the intersection of psychology and physiology Seth was known to many as a pioneer in the burgeoning field of self-experimentation. He was an early contributor to the Quantified Self movement, which owes a huge debt to his thinking. His experiments looked at how to optimize weight loss, mood, sleep, mental speed, balance and even to address specific conditions like acne. He wrote a blog on topics related to health and scientific method. I greatly enjoyed side discussions with Seth at the Ancestral Health Symposium meetings and personal correspondence over the years. This August, both Seth and I were scheduled to talk at AHS in Berkeley. While my talk on myopia will still happen, we will never hear his talk about self-experimentation.
Yet, to pigeonhole Seth as a primarily a self-experimentalist fails to understand what he was really about as a thinker. As a professional research psychologist, he focused on developing “productive explanations” — explanations that help us not only to make sense of an individual surprising observation, but that also make predictions about additional diverse and often novel practical applications. Self-experimentation was one important input, but certainly not his only source of experimental material. Self-experimentation has the virtue of allowing one to do more experiments in less time without spending a lot of money. Self experiments allow you to make incremental progress rapidly, to adjust and learn quickly.
But Seth didn’t stop there He typically synthesized results from many different fields into a coherent explanation. He was not against using data from larger experiments, even controlled double-blind experiments. It’s just that large “designed” experiments sometimes become unwieldy and expensive failures. Simple self-experiments get you started “learning by doing” and often allow you to make rapid progress and weed out untenable hypotheses quickly, before you sink a lot of time and effort into your investigations. The best example of how Seth combined self-experiment with classical science may be how he came up with the Shangri-La Diet, a seemingly wacky–but actually very effective–way of losing weight, safely and without hunger.
I’m writing this post the week before Thanksgiving, to give you something to think about as you are polishing off that last piece of pie….
One of the most common reactions I get to my advice to try intermittent fasting is: I could never do that!
Like the Jackson Browne song “Running on Empty,” the word “fasting” often conjures up dire images of starvation and energy deprivation. Many of you reading this post may have experienced strong hunger pangs, headaches, tiredness, sweating and even shaking or wooziness when going without eating for even part of a day, much less a whole day. So it is natural to extrapolate such experiences into the thought that going without food for a day, or even several hours, would invariably lead to uncomfortable or even dangerous hypoglycermic symptoms. That, together with the negative image of fasting as something unhealthy or associated with eating disorders, leaves most people pale at the thought of even attempting a short fast.
But I tell you, if you don’t try fasting you are missing out on an enjoyable, incredibly energizing experience that will put you in control of your eating and improve your health, your energy and your outlook. Many people, myself included, have learned to fast for up to a day or even longer, on a regular basis and without negative repurcussions. Done correctly, short-term fasting is not dangerous, it’s actually health-promoting and greatly helps to retrain your appetite. If you need to lose weight, the fast helps both in reducing basal insulin and retraining your appetite to be smaller. I’ve written about the benefits of intermittent fasting extensively on this site. Many of the Diet Links listed in the right-hand panel, such as fast-5 and Eat-Stop-Eat, amply document the safety and health benefits of fasting, dispelling the myths about “starvation mode”, slowing of metabolism, and loss of lean muscle mass. So I won’t reiterate here the voluminous evidence supporting the benefits of intermittent fasting. Our bodies are designed to last many days with out food, without great discomfort, and in fact it is beneficial to our health to forgo food periodically. But many of you are asking: Am I really up to this? How do I get started? Read More
You’ve embarked on a new weight loss diet or fitness program. You’ve read a book, become inspired, signed up for a program or health club and what’s more — it’s working. For the first week, two weeks, a month, the weight is coming off, you’re hitting the gym on a regular schedule. You even drop a size or two and garner some compliments from friends.
And then…progress stalls. You’re still eating the same foods, faithfully completing your workouts, but your weight loss stalls, perhaps the scale even goes up a few pounds. The progress you make at the gym similarly maxes out…you can’t lift any more weight, your running speed or distance maxes out…maybe even some soreness or injury sets you back a bit. You’ve hit the dreaded plateau. Sometimes it lasts a few weeks and progress resumes. But it can last months. And it saps your morale because you are not getting any more return on your invested effort. In all likelihood, you give up or cut back, your discipline withers. Your weight goes back up, maybe adding a few pounds on top of where you started, and you cut back on or cut out your exercise program. The genie is back in the bottle.
What causes plateaus? Are they inevitable endpoints in any effort to make progress? Or are they at best temporary way-posts or resting points that you can move beyond with the right approach? The school of thought that says that plateaus are unavoidable indicators of biological limits is called the Set Point theory. I think that the Set Point theory is wrong, and that there is a reliable way to push past plateaus to bring about substantial weight loss and improved fitness.
Posted 23 May 2010 — by Todd
One of the first scientifically rigorous demonstrations of the benefits of hormesis was a 1934 study of calorie restriction (often abbreviated “CR”) in laboratory rats, conducted by Mary Crowell and Clive McCay at Cornell. They found that reducing the calories of rats by 30-50%, supplemented with adequate micro-nutrients, could almost double their lifespans. Later studies found continued lifetime extension with calorie restriction up to 65%. In addition, the rats remained energetic and youthful in appearance, with greatly reduced incidence, and delayed onset, of age-related diseases. This same phenomenon has been observed in a variety of other animals.
Studies on calorie restriction in primates or humans are as yet inconclusive. Controlled primate studies only started in the late 1980s and have yet to be completed, although the preliminary indications are very promising. And in humans it is more difficult to conduct controlled studies for both ethical and compliance reasons. An additional factor to consider is that animals raised post-weaning on calorie restricted diets typically have much smaller adult body sizes that animals not restricted in their eating. Because of the social and physical implications of this consequence, advocates of calorie restricted diets for humans advise that they be started only upon reaching adulthood.
Whether or not a restricted calorie diet extends the human lifespan, the evidence is becoming overwhelming that a nutritionally complete diet with reduced calories has the potential to greatly improve our health, particularly as we age. But is it practical and possible for humans to happily adhere to such a diet?
Want to experience the benefits of hormesis very directly? Take a cold shower! And don’t just try it once, make it a habit and take cold showers daily. I have been doing it daily for the past six months and am loving it!
As one form of hydrotherapy, the health benefits of cold water therapy are numerous. Cold showers provide a gentle form of stress that leads to thermogenesis (internal generation of body heat), turning on the body’s adaptive repair systems to strengthen immunity, enhance pain and stress tolerance, and ward off depression, overcome chronic fatigue syndrome, stop hair loss, and stimulate anti-tumor responses.
A number of recent weight loss methods have been developed that explicitly recognize a close relationship between flavor and appetite. These methods include:
- Flavor-calorie dissociation as advocated by Seth Roberts in his Shangri-La Diet
- Sensory-specific satiety, as advocated in David Katz’s Flavor Point Diet
- Tastants, another approach to sensory-specific satiety, as advertised in Alan Hirsch’s Sensa Weight-Loss Program.
- Odor inhalers, a third approach based on sensory-specific satiety, as described in Alan Hirsch’s book Scentsational Weight Loss, and marketed by him as “diet pens” offered by SlimScents
At first, some of these approaches appear to be mutually incompatible. The Shangri-La theory argues that strong or familiar flavors enhance appetite when they become associated with caloric foods. The other three approaches, by contrast, claim that intense flavors or aromas suppress appetite, based upon the principle of “sensory-specific satiety”, whereby an increase in the intensity of a single flavor or odor induces satiety. However, on closer examination, all of the above theories are consistent with one another, as I will try to show. Furthermore, they each provide some useful clues about how to achieve a long term weight loss and relief from hunger cravings by paying attention to the role of flavor and other food cues. Finally, as I will attempt to persuade you, only one of the above diets is truly a type of Deconditioning Diet that can lead to long term, permanent reduction in appetite, based on the principles of Hormetism.